NGS

WGS400 – YSEQ’s new Whole Genome NGS Specifically for Genealogy Researchers with 400 Base Long Reads

In mid-February 2021, the company YSEQ from Berlin presented its new product, the WGS400. I was very pleased about this, because I have already had very good experiences with the company YSEQ in recent years and they offer some advantages over other companies for me. With the WGS400, they now also offer an NGS (Next Generation Sequencing) that is not only high quality, but also competitively priced and includes everything that is important to me as a DNA genealogy researcher.

Prepare the BAM file for YFull, from a WGS

You don’t upload the raw data BAM file of the NGS test to Yfull yourself, but indicate where it can be downloaded. You can get the link from the provider where you did your test. (FTDNA, YSEQ, FGC). Companies like Dante Labs don’t offer such a link for Yfull directly, so you have to make the required file accessible via a cloud.

YFull – First Steps

Yfull is not a provider of Y-DNA or NGS tests, but an analysis service for NGS with a database in which data from NGS tests are compared and analyzed, regardless of the provider. This allows to compare the results of currently 13 sources. (Commercial companies and scientific studies). The results are presented in the form of a Y-tree in different representations. The kits are presented anonymously and the Y-tree (as well as the mt-tree) is publicly accessible for everyone. This makes it not only an enrichment for the submitters, but also for everyone who is concerned with the topic Y-tree (as well as mt-tree).

Verify relationship in paternal line, with known terminal SNP and private „novel“ SNPs from NGS

f you wanted to compare the Y-DNA of two men, you used Y-STR tests with as many markers as possible. If one or more NGS (Next Generation Sequencing) are available, a new method can be used to determine the relationship of two men in a purely paternal line using “young” SNPs. Your youngest SNPs are those that have only been detected in your sample. These are called “Novel SNPs” or “Private SNPs”.
This method is made possible by the company YSEQ.net and the possibility to actually test any SNP that can be tested with the Sanger method for little money after you “wish” for it.

NGS – Take part at the Y-tree

Since my first Y-DNA test I have been fascinated by the Y trees. That’s why I support these projects and have already contributed some NGS. In the beginning I couldn’t imagine much of it. What, when, where and why happens this and that? In the meantime, I can answer some questions. Here is a small overview of what happens when you participate in a Y-tree.
But there are also a few more ways to support haplogroup projects. By donating, even if it is “only” the raw data of the existing test.